Dazukibart

• CAT Number: I040386
• CAS Number: 2639474-65-8
• Purity: ≥95%

Dazukibart(CAT: I040386)is a humanized IgG1 monoclonal antibody that selectively neutralizes interferon‑beta (IFN‑β), a mediator implicated in type I interferon–driven autoimmune conditions. It is being developed for dermatomyositis, polymyositis, and cutaneous forms of lupus. In a Phase II clinical trial for moderate-to-severe dermatomyositis, monthly infusions (150–600 mg) led to robust reductions in disease activity and skin symptoms, and the treatment was well tolerated. Dazukibart is now in Phase III long-term studies evaluating its safety, efficacy, and durability in idiopathic inflammatory myopathies. Supplied at high purity, it is ideal for research in autoimmunity, immune signaling, and inflammatory disease pathways.