For research use only. Not for therapeutic Use.
DAMGO TFA (Cat No.:I018202) is a highly selective synthetic peptide agonist for the μ-opioid receptor. As a stable analog of enkephalins, it binds with high affinity and potency, making it an essential tool for investigating opioid receptor pharmacology, pain modulation, and receptor-mediated signaling. DAMGO is widely applied in neuroscience, analgesia research, and studies of G protein–coupled receptor (GPCR) mechanisms. Supplied as a trifluoroacetate (TFA) salt, it offers stability and consistency in experimental settings, enabling reliable characterization of μ-opioid receptor–dependent pathways.
| CAS Number | 950492-85-0 |
| Synonyms | (2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-methylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide;2,2,2-trifluoroacetic acid |
| Molecular Formula | C28H36F3N5O8 |
| Purity | ≥95% |
| IUPAC Name | (2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-methylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide;2,2,2-trifluoroacetic acid |
| InChI | InChI=1S/C26H35N5O6.C2HF3O2/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18;3-2(4,5)1(6)7/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36);(H,6,7)/t17-,21+,22+;/m1./s1 |
| InChIKey | NIGIQPUQVVEMTD-NJUGUJQKSA-N |
| SMILES | C[C@H](C(=O)NCC(=O)N(C)[C@@H](CC1=CC=CC=C1)C(=O)NCCO)NC(=O)[C@H](CC2=CC=C(C=C2)O)N.C(=O)(C(F)(F)F)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
