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Cycloguanil pamoate

Cycloguanil pamoate

  • CAT Number: I006335
  • CAS Number: 609-78-9
  • Molecular Formula: C45H44Cl2N10O6
  • Molecular Weight: 891.811
  • Purity: ≥95%
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Cycloguanil pamoate (Cat. No: I006335), also known as 2-Naphthalenecarboxylic acid, can be used as a standard for pharmaceutical development research, mainly for scientific research.

Catalog Number I006335
CAS Number 609-78-9
Molecular Formula

C45H44Cl2N10O6

Purity 95%
Solubility Soluble in DMSO, not in water
Storage 0 - 4°C for short term ,or -20 °C for long term
IUPAC Name 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid;1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine
InChI InChI=1S/C23H16O6.2C11H14ClN5/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;2*1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2*3-6H,1-2H3,(H4,13,14,15,16)
InChIKey LUNRMKZYOGNOTR-UHFFFAOYSA-N
SMILES CC1(N=C(N=C(N1C2=CC=C(C=C2)Cl)N)N)C.CC1(N=C(N=C(N1C2=CC=C(C=C2)Cl)N)N)C.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O
Reference

</br>1:Activities of respository preparations of cycloguanil pamoate and 4,4/’-diacetyldiaminodiphenylsulfone, alone and in combination, against infections with Plasmodium cynomolgi in rhesus monkeys. Schmidt LH, Rossan RN.Antimicrob Agents Chemother. 1984 Nov;26(5):611-42. PMID: 6393864 Free PMC Article</br>2:Treatment of cutaneous leishmaniasis with cycloguanil pamoate. Ardehali M.Int J Dermatol. 1974 Jan-Feb;13(1):26-8. No abstract available. PMID: 4813519 </br>3:A field trial of the effectiveness of cycloguanil pamoate in Rhodesia. Harwin RM.Cent Afr J Med. 1973 Jan;19(1):9-12. No abstract available. PMID: 4576484 </br>4:[Therapy of cutaneous leishmaniasis (Leishmania tropica) with cycloguanil pamoate]. Reinhard M, Wacker H.Dtsch Med Wochenschr. 1970 Nov 20;95(47):2380-2. German. No abstract available. PMID: 5481970 </br>5:Field trial of cycloguanil pamoate in the treatment and suppression of malaria in Nigerian school children: a preliminary report. Fasan PO.Trans R Soc Trop Med Hyg. 1970;64(6):839-49. No abstract available. PMID: 5495634 </br>6:The treatment of cutaneous leishmaniasis in Iraq with cycloguanil pamoate. Salem HH, Elkomy HM, el-Allaf G.Trans R Soc Trop Med Hyg. 1969;63(3):388-92. No abstract available. PMID: 5795162 </br>7:Cycloguanil pamoate in the treatment of cutaneous leishmaniasis. Initial trials in Panamá. Johnson CM.Am J Trop Med Hyg. 1968 Nov;17(6):819-22. No abstract available. PMID: 5726132 </br>8:Treatment of American cutaneous leishmaniasis with cycloguanil pamoate. Walton BC, Person DA, Ellman MH, Bernstein R.Am J Trop Med Hyg. 1968 Nov;17(6):814-7. No abstract available. PMID: 4302275 </br>9:Treatment of American dermal leishmaniasis with cycloguanil pamoate. Pena Chavarria A, Kotcher E, Lizano C.Trans R Soc Trop Med Hyg. 1968;62(4):550-5. No abstract available. PMID: 5671542 </br>10:Evaluation of CI-564, A 1:1 mixture of cycloguanil pamoate (CI-501) and 4,4/’-diacetylaminodiphenylsulfone (CI-556), against multiresistant falciparum malarias. Chin W, Contacos PG, Coatney GR, Jeter MH, Alpert E.Am J Trop Med Hyg. 1967 Sep;16(5):580-4. No abstract available. PMID: 4861322

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