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CP-74006

CP-74006

  • CAT Number: I011879
  • CAS Number: 4943-86-6
  • Molecular Formula: C13H11ClN2O
  • Molecular Weight: 246.69
  • Purity: ≥95%
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CP-74006 (Cat.No:I011879) is a selective D5D inhibitor. CP-74006 potently blocks the Delta5D activity with an IC(50) value of 20 nM and simplifies the metabolism of [1-(14)C]-alpha-linolenate (C18:3, cis-9,12,15) by accumulating (14)C-eicosatetraenoic acid (C20:4, cis-8,11,14,17) as the major (14)C-eicosatrienoic acid (C20:3, cis-11,14,17) and (14)C-docosatetraenoic acid (C22:4, cis-10,13,16,19) as the minor metabolites through Delta6 desaturation and elongation.

Catalog Number I011879
CAS Number 4943-86-6
Molecular Formula

C13H11ClN2O

Purity 95%
Target D5D inhibitor
Solubility Soluble in DMSO
Storage Store at 2-8 °C
IUPAC Name 2-amino-N-(4-chlorophenyl)benzamide
InChI InChI=1S/C13H11ClN2O/c14-9-5-7-10(8-6-9)16-13(17)11-3-1-2-4-12(11)15/h1-8H,15H2,(H,16,17)
InChIKey RHCJFZKQYODIDI-UHFFFAOYSA-N
SMILES C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)Cl)N
Reference

</br>1: Zhang L, Ramtohul Y, Gagné S, Styhler A, Wang H, Guay J, Huang Z. A</br> multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6,</br> and delta-9 desaturase and elongase inhibitors. J Biomol Screen. 2010</br> Feb;15(2):169-76. doi: 10.1177/1087057109356208. Epub 2010 Jan 19. PubMed PMID:</br> 20086206.</br> </br>

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