Clindamycin inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.<br />
Clindamycin is a semisynthetic analogue of lincomycin. Clindamycin primarily inhibits the initiation of peptide chain synthesis by deregulating enzyme-catalyzed initiation of peptide bounds. Clindamycin appears to have a modest effect on protein synthesis by certain mammalian cells.<br />
Clindamycin (50mg/kg daily administrated by intramuscular) increases the survival rate of monkeys infected with penicillin-resistant <i>S. aureu</i> to 87.5% (7/8).
Catalog Number | A000300 |
CAS Number | 18323-44-9 |
Synonyms | NA |
Molecular Formula | C18H33ClN2O5S |
Purity | 98 |
Storage | 3 years -20C powder |
InChIKey | KDLRVYVGXIQJDK-AWPVFWJPSA-N |