Clenbuterol Hydrochloride

• CAT Number: R005984
• CAS Number: 21898-19-1
• Molecular Formula: C12H18Cl2N2O • HCl
• Molecular Weight: 313.7
• Purity: ≥95%
• Target: Adrenergic Receptor
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: 1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanol;hydrochloride
• InChI: InChI=1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H
• InChIKey: OPXKTCUYRHXSBK-UHFFFAOYSA-N
• SMILES: CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)Cl)O.Cl

Clenbuterol Hydrochloride (Cat.No:R005984) is a sympathomimetic β2-adrenoceptor agonist that has been used as a bronchodilator in the treatment of pulmonary diseases such as asthma. At higher doses, clenbuterol acts as an anabolic steroid, favoring skeletal muscle protein synthesis at the expense of fat deposition.

Reference

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2:Selection and Application of ssDNA Aptamers against Clenbuterol Hydrochloride Based on ssDNA Library Immobilized SELEX. Duan N, Gong W, Wu S, Wang Z.J Agric Food Chem. 2017 Mar 1;65(8):1771-1777. doi: 10.1021/acs.jafc.6b04951. Epub 2017 Feb 21. PMID: 28161951
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4:Highly sensitive fluorescent probe for clenbuterol hydrochloride detection based on its catalytic oxidation of eosine Y by NaIO4. Liu J, Liu ZB, Huang Q, Lin CQ, Lin X.J Fluoresc. 2014 Sep;24(5):1495-501. doi: 10.1007/s10895-014-1435-7. Epub 2014 Aug 27. PMID: 25155629
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6:Rapid screening of clenbuterol hydrochloride in chicken samples by molecularly imprinted matrix solid-phase dispersion coupled with liquid chromatography. Qiao F, Du J.J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Apr 1;923-924:136-40. PMID: 23500358
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8:Solid substrate-room temperature phosphorimetry for the determination of residual clenbuterol hydrochloride based on the catalysis of sodium periodate oxidizing eosine Y. Liu J, Zeng L, Li Z, Gao F, Huang X, Li F, Lin H.Anal Chim Acta. 2009 Apr 6;638(1):69-74. doi: 10.1016/j.aca.2009.02.007. Epub 2009 Feb 12. PMID: 19298881
9:[Use of ultrasensitive time-resolved fluoroimmunoassay for rapid detection of clenbuterol hydrochloride in urine]. Shi J, Huang B, Zhang LF, Mi XL, Xu GR, Jin J.Wei Sheng Yan Jiu. 2006 Nov;35(6):798-801. Chinese. PMID: 17290771
10:[Enantiomeric resolution of clenbuterol hydrochloride using (2R, 3R)-Dicyclohexyl tartrate impregnated thin layer chromatography]. Yu J, Liu S, Huang K, Jiao F, Peng X.Se Pu. 2005 Nov;23(6):687. Chinese. No abstract available. PMID: 16499011