CONTACT US
Home > Reference Standards> > Clausine Z
Clausine Z

Clausine Z

  • CAT Number: R014956
  • CAS Number: 866111-14-0
  • Molecular Formula: C13H9NO3
  • Molecular Weight: 227.219
  • Purity: ≥95%
Inquiry Now

Clausine Z(cas 866111-14-0) exhibits inhibitory activity against cyclin-dependent kinase 5 (CDK5) and shows protective effects on cerebellar granule neurons in vitro.

Catalog Number R014956
CAS Number 866111-14-0
Synonyms

1,6-dihydroxy-9H-carbazole-3-carbaldehyde; ClausineZ; Clausine-Z;

Molecular Formula

C13H9NO3

Purity 95%
Storage -20°C
IUPAC Name 1,6-dihydroxy-9H-carbazole-3-carbaldehyde
InChI InChI=1S/C13H9NO3/c15-6-7-3-10-9-5-8(16)1-2-11(9)14-13(10)12(17)4-7/h1-6,14,16-17H
InChIKey FKDULSCBYNXNMP-UHFFFAOYSA-N
SMILES C1=CC2=C(C=C1O)C3=CC(=CC(=C3N2)O)C=O
Reference

1. Pharmazie. 2005 Aug;60(8):637-9.
<br>
Clausine Z, a new carbazole alkaloid from Clausena excavata with inhibitory
activity on CDK5.
<br>
Potterat O(1), Puder C, Bolek W, Wagner K, Ke C, Ye Y, Gillardon F.
<br>
Author information: <br>
(1)Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
[email protected]
<br>
A new carbazole alkaloid, named clausine Z, has been isolated from the stems and
leaves of Clausena excavata Burm. (Rutaceae). Its structure was established by
spectroscopic methods. The compound exhibits inhibitory activity against
cyclin-dependent kinase 5 (CDK5) and shows protective effects on cerebellar
granule neurons in vitro.

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!