CL 316243 Disodium Salt

  • CAT Number: R014576
  • CAS Number: 138908-40-4
  • Molecular Formula: C20H18ClNNa2O7
  • Molecular Weight: 465.794
  • Purity: ≥95%
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CL 316,243 is a β<sub>3</sub>-adrenoceptor agonist (EC<sub>50</sub> = 3 nM) that is &gt;10,000-fold selective over β<sub>1</sub> and β<sub>2</sub>. It causes a rapid decrease in blood glucose level in mice and has been used to study the induction of brown adipocytes and to increase thermogenesis in a mouse model of dietary obesity.

Catalog Number R014576
CAS Number 138908-40-4
Molecular Formula

C20H18ClNNa2O7

Purity 95%
Storage -20°C
IUPAC Name disodium;5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate
InChI InChI=1S/C20H20ClNO7.2Na/c1-11(22-10-15(23)13-3-2-4-14(21)9-13)7-12-5-6-16-17(8-12)29-20(28-16,18(24)25)19(26)27;;/h2-6,8-9,11,15,22-23H,7,10H2,1H3,(H,24,25)(H,26,27);;/q;2*+1/p-2/t11-,15+;;/m1../s1
InChIKey FUZBPOHHSBDTJQ-CFOQQKEYSA-L
SMILES CC(CC1=CC2=C(C=C1)OC(O2)(C(=O)[O-])C(=O)[O-])NCC(C3=CC(=CC=C3)Cl)O.[Na+].[Na+]

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