CONTACT US
Home > Reference Standards>P-glycoprotein> > Chrysosplenetin
Chrysosplenetin

Chrysosplenetin

  • CAT Number: R004000
  • CAS Number: 603-56-5
  • Molecular Formula: C19H18O8
  • Molecular Weight: 374.34
  • Purity: ≥95%
Inquiry Now

Chrysosplenetin（Cat No.:R004000） is a polymethoxylated flavonoid present in Artemisia annua and other Chinese herbal medicines. It possesses inhibitory effects on P-glycoprotein (P-gp) activity and can reverse the upregulation of P-gp and MDR1 levels induced by artemisinin (ART). Chrysosplenetin has been shown to enhance the plasma levels of ART and improve its antimalarial efficacy in rats. This effect is attributed, at least in part, to its noncompetitive inhibition of rat CYP3A. These findings suggest the potential of chrysosplenetin as an adjuvant in malaria treatment.

Catalog Number R004000
CAS Number 603-56-5
Molecular Formula

C19H18O8

Purity 95%
Storage 2-8°C
IUPAC Name 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxychromen-4-one
InChI InChI=1S/C19H18O8/c1-23-11-7-9(5-6-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3
InChIKey NBVTYGIYKCPHQN-UHFFFAOYSA-N
SMILES COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)OC)OC)O)OC)O

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!