Chrysophanol 8-O-glucoside

• CAT Number: R041523
• CAS Number: 13241-28-6
• Molecular Formula: C21H20O9
• Molecular Weight: 416.38
• Purity: ≥95%
• Synonyms: 1-hydroxy-3-methyl-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione
• InChI: InChI=1S/C21H20O9/c1-8-5-10-14(11(23)6-8)18(26)15-9(16(10)24)3-2-4-12(15)29-21-20(28)19(27)17(25)13(7-22)30-21/h2-6,13,17,19-23,25,27-28H,7H2,1H3/t13-,17-,19+,20-,21-/m1/s1
• InChIKey: WMMOMSNMMDMSRB-JNHRPPPUSA-N
• SMILES: CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3OC4C(C(C(C(O4)CO)O)O)O

Chrysophanol 8-O-glucoside(CAT: R041523) is an anthraquinone glycoside derived from chrysophanol, a major bioactive constituent of plants such as Rheum palmatum (rhubarb) and Polygonum multiflorum. The attachment of a glucose moiety at the 8-hydroxyl position enhances its solubility and influences its pharmacokinetic behavior. This compound has been reported to exhibit diverse biological activities, including anti-inflammatory, antioxidant, hepatoprotective, and neuroprotective effects. In traditional herbal medicine research, chrysophanol 8-O-glucoside is studied for its role in liver health, gastrointestinal function, and potential in protecting against oxidative stress–related disorders. It also serves as an important phytochemical marker in quality control of medicinal rhubarb extracts.