CHR 6494 trifluoroacetate

• CAT Number: I011168
• CAS Number: 1458630-17-5
• Molecular Formula: C18H17F3N6O2
• Molecular Weight: 406.369
• Purity: ≥95%
• Solubility: Soluble to 100 mM in DMSO
• Storage: Store at +4C
• IUPAC Name: 3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C16H16N6.C2HF3O2/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13;3-2(4,5)1(6)7/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20);(H,6,7)
• InChIKey: ILWYDZNXJQESDI-UHFFFAOYSA-N
• SMILES: CCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1.C(=O)(C(F)(F)F)O

CHR 6494 trifluoroacetate(CAT: I011168) emerges as a remarkable achievement in kinase inhibition research and potential cancer therapy. As a potent and selective inhibitor of haspin kinase, CHR 6494 trifluoroacetate demonstrates its prowess by effectively targeting this specific kinase with an impressive IC50 of 2 nM. Notably, it showcases selectivity over a panel of 27 other protein kinases, including Aurora B kinase.