Cholic Acid-d5

• CAT Number: C000842
• CAS Number: 53007-09-3
• Molecular Formula: C₂₄H₃₅D₅O₅
• Molecular Weight: 413.6
• Purity: ≥95%
• Solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
• Storage: Store at -20°C
• IUPAC Name: (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-2,2,3,4,4-pentadeuterio-3,7,12-trihydroxy-10,13-dimethyl-1,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid
• InChI: InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1/i8D2,10D2,15D
• InChIKey: BHQCQFFYRZLCQQ-VRLVFLRJSA-N
• SMILES: CC(CCC(=O)O)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C

Cholic Acid-d5 (Cat No.:C000842) is a deuterium-labeled form of cholic acid, a primary bile acid produced in the liver and essential for digestion and lipid absorption in the intestine. The “d5” notation indicates that five hydrogen atoms in the molecule are replaced with deuterium, a stable isotope of hydrogen. This labeling allows for precise isotope tracing in research and analytical applications. Cholic Acid-d5 is used as an internal standard in mass spectrometry and metabolic studies, facilitating accurate quantification and identification of cholic acid and related bile acids in biological samples, aiding research in hepatology and lipid metabolism.

Reference

Nomoto, M., et al.: Biol. Pharm. Bull., 32, 172 (2009), Simonsen, H., et al.: J. Agric. Food Chem., 57, 2056 (2009), Miyata, M., et al.: Drug Metab. Disposition, 37, 338 (2009),