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Chlorprothixene Hydrochloride

Chlorprothixene Hydrochloride

  • CAT Number: R012205
  • CAS Number: 6469-93-8
  • Molecular Formula: C18H18ClNS • HCl
  • Molecular Weight: 352.3
  • Purity: ≥95%
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Chlorprothixene hydrochloride（Cat No.:R012205） is a potent dopamine and histamine receptor antagonist that binds to human D1, D2, D3, D5, and H1 receptors with high affinity, indicated by Ki values of 18 nM, 2.96 nM, 4.56 nM, 9 nM, and 3.75 nM, respectively. Due to its interactions with these receptors, it exhibits antipsychotic effects. This compound’s ability to block dopamine and histamine receptors makes it valuable in managing psychotic disorders and related conditions, providing relief from symptoms such as hallucinations and delusions.

Catalog Number R012205
CAS Number 6469-93-8
Molecular Formula

C18H18ClNS • HCl

Purity 95%
Target Dopamine Receptor
Solubility Soluble in DMSO
Storage Store at 2-8°C
IUPAC Name (3Z)-3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride
InChI InChI=1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;
InChIKey YWKRLOSRDGPEJR-KIUKIJHYSA-N
SMILES CN(C)CCC=C1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl

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