Chamaejasmine

• CAT Number: I042452
• CAS Number: 69618-96-8
• Molecular Formula: C30H22O10
• Molecular Weight: 542.49
• Purity: ≥95%
• Synonyms: (2R,3S)-3-[(2R,3S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
• InChI: InChI=1S/C30H22O10/c31-15-5-1-13(2-6-15)29-25(27(37)23-19(35)9-17(33)11-21(23)39-29)26-28(38)24-20(36)10-18(34)12-22(24)40-30(26)14-3-7-16(32)8-4-14/h1-12,25-26,29-36H/t25-,26-,29+,30+/m1/s1
• InChIKey: RNQBLQALVMHBKH-HHGOQMMWSA-N
• SMILES: C1=CC(=CC=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)C4C(OC5=CC(=CC(=C5C4=O)O)O)C6=CC=C(C=C6)O)O

Chamaejasmine (Cat No.: I042452) is a naturally occurring biflavonoid compound isolated from Stellera chamaejasme and related plant species. It exhibits a wide range of biological activities, including anti-cancer, anti-inflammatory, and anti-microbial effects. Chamaejasmine has been shown to induce apoptosis and inhibit proliferation in various cancer cell lines, primarily through modulation of pathways such as PI3K/Akt and MAPK. It is a valuable compound in pharmacological research for its potential as a lead molecule in the development of novel therapeutic agents from natural products.

Reference

[1]. Yang D, et al. The role of chamaejasmine in cellular apoptosis and autophagy in MG-63 cells. Biosci Rep. 2019 Jan 15;39(1):BSR20181707.
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