CH 141

• CAT Number: I006077
• CAS Number: 78279-88-6
• Molecular Formula: C19H21N3O
• Molecular Weight: 307.397
• Purity: ≥95%
• Synonyms: CH 141; CH-141; CH141; Pthiqdo.;6-((3,4-dihydroisoquinolin-2(1H)-yl)methyl)-3-phenyl-5,6-dihydro-2H-1,2,4-oxadiazine
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• IUPAC Name: 6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-3-phenyl-5,6-dihydro-2H-1,2,4-oxadiazine
• InChI: InChI=1S/C19H21N3O/c1-2-7-16(8-3-1)19-20-12-18(23-21-19)14-22-11-10-15-6-4-5-9-17(15)13-22/h1-9,18H,10-14H2,(H,20,21)
• InChIKey: GWAKPCRBHTWEKQ-UHFFFAOYSA-N
• SMILES: C1CN(CC2=CC=CC=C21)CC3CN=C(NO3)C4=CC=CC=C4

CH 141 is a new type of peripheral vasodilator.

Reference

1:[Study of the absorption of a new peripheral vasodilator compound (CH-141) by in vitro and in vivo methods. 2. Pharmacokinetic study of the compound]. Szemere L, Mezei J, Küttel S, Marton S, Rácz I.Acta Pharm Hung. 1987 Mar;57(1-2):27-33. Hungarian. No abstract available. PMID: 3591339 2:[A new type of peripheral vasodilator, the compound CH-141 in solution. III. Decomposition kinetics of CH-141]. Kovács P, Plachy J, Szemere L, Rácz I.Acta Pharm Hung. 1985 May;55(3):107-13. Hungarian. No abstract available. PMID: 4036625 3:[New type of peripheral vasodilator, the compound CH-141 studied in solution. II. Mechanism of thermal decomposition and identification of decomposition products]. Kovács P, Plachy J, Szemere L, Rácz I.Acta Pharm Hung. 1985 Mar;55(2):85-91. Hungarian. No abstract available. PMID: 4013758 4:[Study of the absorption of a new peripheral vasodilator (CH-141) by in vitro and in vivo methods. I. In vitro model of liquid transport]. Szemere L, Marton S.Acta Pharm Hung. 1985 Mar;55(2):59-67. Hungarian. No abstract available. PMID: 4013755 5:[Ch-141, a new drug with peripheral vasodilator action studied in solution. I. Analytic study of the compound with reference to the selectivity of the methods for stability tests]. Kovács P, Szemere L, Plachy J, Rácz I.Acta Pharm Hung. 1985 Jan;55(1):1-7. Hungarian. No abstract available. PMID: 4013752