Ceranib1（Cat No.:I010960）is a small-molecule inhibitor of acid ceramidase, an enzyme that hydrolyzes ceramide into sphingosine and fatty acid. By blocking this activity, Ceranib1 increases intracellular ceramide levels, promoting apoptosis and reducing cell survival. It has been studied in cancer research for its ability to sensitize tumor cells to chemotherapeutics and radiotherapy, as well as in inflammation and metabolic disease models where sphingolipid signaling is dysregulated. Ceranib1 is a valuable pharmacological tool for probing ceramide metabolism and exploring therapeutic strategies targeting sphingolipid pathways in disease.