For research use only. Not for therapeutic Use.
Cemdisiran（Cat No.:I044003）is an investigational RNA interference (RNAi) therapy designed to target and silence the production of serum amyloid A (SAA), a protein involved in inflammation and amyloidosis. By inhibiting SAA expression, Cemdisiran aims to reduce inflammation and prevent the accumulation of amyloid deposits, which can damage organs and tissues. It is being studied for its potential to treat conditions like hereditary transthyretin amyloidosis (hATTR) and other amyloid-related diseases. Cemdisiran offers a novel therapeutic approach to managing these conditions by specifically targeting the underlying molecular mechanisms of amyloidosis.
| CAS Number | 1639264-46-2 |
| Synonyms | [(2S,4R)-1-[12-[[1,3-bis[3-[3-[5-[(2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypentanoylamino]propylamino]-3-oxopropoxy]-2-[[3-[3-[5-[(2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypentanoylamino]propylamino]-3-oxopropoxy]methyl]propan-2-yl]amino]-12-oxododecanoyl]-4-hydroxypyrrolidin-2-yl]methyl dihydrogen phosphate |
| Molecular Formula | C542H711F17N169O330P45S6 |
| Purity | ≥95% |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
