CCT241736

• CAT Number: I019786
• CAS Number: 1402709-93-6
• Molecular Formula: C₂₂H₂₃Cl₂N₇
• Molecular Weight: 456.37
• Purity: ≥95%
• Storage: Store at -20°C

CCT241736（Cat No.:I019786）is a chemical compound that acts as a selective and potent inhibitor of checkpoint kinase 1 (Chk1). Chk1 plays a crucial role in DNA damage response and repair in cancer cells, and its inhibition can lead to cell death and reduced tumor growth. CCT241736 has shown promising results in preclinical studies as an antitumor agent and may have potential as a cancer therapy.

Reference

[1]. Bavetsias V, et al. Optimization of imidazo[4,5-b]pyridine-based kinase inhibitors: identification of a dual FLT3/Aurora kinase inhibitor as an orally bioavailable preclinical development candidate for the treatment of acute myeloid leukemia. J Med Chem. 2012 Oct 25;55(20):8721-34.