CC-671

• CAT Number: I013006
• CAS Number: 1618658-88-0
• Molecular Formula: C₂₈H₂₈N₆O₄
• Molecular Weight: 512.56
• Purity: ≥95%
• Target: CDK
• Solubility: DMSO
• Storage: Store at -20°C
• IUPAC Name: 4-[[4-cyclopentyloxy-5-(2-methyl-1,3-benzoxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methylbenzamide
• InChI: InChI=1S/C28H28N6O4/c1-15-31-21-10-8-16(12-23(21)37-15)19-14-30-25-24(19)27(38-18-6-4-5-7-18)34-28(33-25)32-20-11-9-17(26(35)29-2)13-22(20)36-3/h8-14,18H,4-7H2,1-3H3,(H,29,35)(H2,30,32,33,34)
• InChIKey: CWJLAVRXVFHDSJ-UHFFFAOYSA-N
• SMILES: CC1=NC2=C(O1)C=C(C=C2)C3=CNC4=C3C(=NC(=N4)NC5=C(C=C(C=C5)C(=O)NC)OC)OC6CCCC6

CC-671（Cat No.:I013006） is a small molecule inhibitor that targets the protein ERAP1, which is involved in processing and presenting peptides on the surface of cells. By inhibiting ERAP1, CC-671 can modulate the immune system and potentially be used to treat autoimmune disorders and cancer. CC-671 is a promising drug candidate that may offer new treatment options for patients with immune-related disorders.

Reference

[1]. Riggs JR, et al. The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatmentof Triple Negative Breast Cancer Initiated from a Phenotypic Screen. J Med Chem. 2017 Nov 9;60(21):8989-9002.