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Catharanthine

Catharanthine

  • CAT Number: A000201
  • CAS Number: 2468-21-5
  • Molecular Formula: C₂₁H₂₄N₂O₂
  • Molecular Weight: 336.43
  • Purity: ≥95%
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Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.<br>Catharanthine evokes a concentration-dependent attenuation of carbachol responses in the rat ileum preparation, producing rightward curve displacements and decreases in maximal agonist responses. The mixture of serpentine, plus ajmalicine and catharanthine reveals a concentration-dependent inhibitory effect of acethylcholinesterase (AchE), with an IC50 at ca. 2.25 μg/mL.

Catalog Number A000201
CAS Number 2468-21-5
Molecular Formula

C₂₁H₂₄N₂O₂

Purity 95%
Target nicotinic receptor
Storage 3 years -20C powder
InChI InChI=1S/C21H24N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,10,13,19,22H,3,8-9,11-12H2,1-2H3
InChIKey CMKFQVZJOWHHDV-UHFFFAOYSA-N
SMILES CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC

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