Casdozokitug

• CAT Number: I040392
• CAS Number: 2643331-37-5
• Purity: ≥95%

Casdozokitug(CAT: I040392) is a fully human IgG1κ monoclonal antibody engineered to target CLEC12A, an inhibitory C-type lectin receptor expressed on myeloid leukemia and myeloid-derived suppressor cells. By blocking CLEC12A signaling, Casdozokitug enhances antigen presentation and restores T cell–mediated anti-tumor immunity. It is currently being evaluated in early-stage clinical trials for acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Preclinical studies demonstrate potent immune activation, reduced leukemic burden, and minimal off-target effects. Supplied at high purity, Casdozokitug is ideal for research in hematologic malignancies, myeloid immunomodulation, and antibody-based immunotherapy development.