Cannabinor

• CAT Number: I005533
• CAS Number: 573981-31-4
• Molecular Formula: C28H38O6
• Molecular Weight: 470.606
• Purity: ≥95%
• Synonyms: PRS-211375; PRS-375; PRS211375; PRS375; PRS 211375; PRS 375; Cannabinor;(E)-4-(2-((1S,2S,5S)-6,6-dimethyl-4-oxobicyclo[3.1.1]heptan-2-yl)-3-hydroxy-5-(2-methyloctan-2-yl)phenoxy)-4-oxobut-2-enoic acid
• Target: annabinoid CB2 agonist
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: (E)-4-[2-[(1S,2S,5S)-6,6-dimethyl-4-oxo-2-bicyclo[3.1.1]heptanyl]-3-hydroxy-5-(2-methyloctan-2-yl)phenoxy]-4-oxobut-2-enoic acid
• InChI: InChI=1S/C28H38O6/c1-6-7-8-9-12-27(2,3)17-13-22(30)26(23(14-17)34-25(33)11-10-24(31)32)18-15-21(29)20-16-19(18)28(20,4)5/h10-11,13-14,18-20,30H,6-9,12,15-16H2,1-5H3,(H,31,32)/b11-10+/t18-,19-,20+/m0/s1
• InChIKey: GSTZHANFXAKPSE-MXTREEOPSA-N
• SMILES: CCCCCCC(C)(C)C1=CC(=C(C(=C1)OC(=O)C=CC(=O)O)C2CC(=O)C3CC2C3(C)C)O

Cannabinor is a cannabinoid CB2 agonist potentially for the treatment of partial urethral obstruction

Reference

1:Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. Gratzke C, Streng T, Stief CG, Alroy I, Limberg BJ, Downs TR, Rosenbaum JS, Hedlund P, Andersson KE.J Urol. 2011 Feb;185(2):731-6. doi: 10.1016/j.juro.2010.09.080. Epub 2010 Dec 18. PMID: 21168864 2:Effects of cannabinor, a novel selective cannabinoid 2 receptor agonist, on bladder function in normal rats. Gratzke C, Streng T, Stief CG, Downs TR, Alroy I, Rosenbaum JS, Andersson KE, Hedlund P.Eur Urol. 2010 Jun;57(6):1093-100. doi: 10.1016/j.eururo.2010.02.027. Epub 2010 Mar 1. PMID: 20207474