Camostat mesylate

• CAT Number: I004239
• CAS Number: 59721-29-8
• Molecular Formula: C20H22N4O5 • CH3SO3H
• Molecular Weight: 494.5
• Purity: ≥95%
• Target: Trypsin-like protease
• Solubility: 10 mM in DMSO, 10 mM in H2O
• Storage: 3 years -20C powder
• InChIKey: FSEKIHNIDBATFG-UHFFFAOYSA-N

Camostat mesylate (CAT: I004239), also known as FOY305 or FOY-S980, functions as a trypsin-like protease inhibitor. Trypsin is an enzyme that plays a significant role in the digestion of proteins and other biological processes. By inhibiting trypsin-like proteases, camostat mesylate interferes with proteolytic activities, which has implications in various physiological and pathological contexts.

Reference

[1]. Okuno, M., et al., Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta. Gastroenterology, 2001. 120(7): p. 1784-800.
[2]. Yamamoto, A., et al., Effects of various protease inhibitors on the intestinal absorption and degradation of insulin in rats. Pharm Res, 1994. 11(10): p. 1496-500.
[3]. Gibo, J., et al., Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. Lab Invest, 2005. 85(1): p. 75-89.