Calcipotriene

  • CAT Number: M026875
  • CAS Number: 112828-00-9
  • Molecular Formula: C27H40O3 · H2O
  • Molecular Weight: 412.6
  • Purity: ≥95%
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Calcipotriol (hydrate) is a low-<wbr></wbr>calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D<sub>3</sub>). Binding of calcipotriol (hydrate) to the VDR increases AP-<wbr></wbr>1, a transcription factor important for keratinocyte differentiation, and reduces expression of JunB protein, a transcriptional activator in the inflammatory response. Calcipotriol (hydrate) also induces expression of thymic stromal lymphopoietin, which triggers T-<wbr></wbr>cell differentiation in keratinocytes.

Catalog Number M026875
CAS Number 112828-00-9
Molecular Formula

C27H40O3 · H2O

Purity 95%
Storage -20°C
InChIKey XBKHACNRWFKJNC-MANNPBRJSA-N

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