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'CAGED GTP

'CAGED GTP

  • CAT Number: M113522
  • CAS Number: 125455-57-4
  • Molecular Formula: C18H21N6Na2O16P3
  • Molecular Weight: 716.293
  • Purity: ≥95%
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<span style="color:#000000;"><span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;">&#39;CAGED GTP(CAS&nbsp;125455-57-4) is a photolabile derivative of GTP. Irradiation with a short light pulse of 360 nm wavelength releases the parent compound from its cage producing a concentration jump of GTP.</span></span></span>

Catalog Number M113522
CAS Number 125455-57-4
Molecular Formula

C18H21N6Na2O16P3

Purity 95%
Storage -20°C
IUPAC Name disodium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [hydroxy-[1-(2-nitrophenyl)ethoxy]phosphoryl] phosphate
InChI InChI=1S/C18H23N6O16P3.2Na/c1-8(9-4-2-3-5-10(9)24(28)29)38-42(32,33)40-43(34,35)39-41(30,31)36-6-11-13(25)14(26)17(37-11)23-7-20-12-15(23)21-18(19)22-16(12)27;;/h2-5,7-8,11,13-14,17,25-26H,6H2,1H3,(H,30,31)(H,32,33)(H,34,35)(H3,19,21,22,27);;/q;2*+1/p-2/t8?,11-,13-,14-,17-;;/m1../s1
InChIKey CALBQCHIEXMHHD-UFPGFHDMSA-L
SMILES CC(C1=CC=CC=C1[N+](=O)[O-])OP(=O)(O)OP(=O)([O-])OP(=O)([O-])OCC2C(C(C(O2)N3C=NC4=C3NC(=NC4=O)N)O)O.[Na+].[Na+]
Reference

1.<span style="font-family: Arial, sans-serif; font-size: 13px;">Schlichting, Ilme, et al. &quot;Biochemical and crystallographic characterization of a complex of c-Ha-ras p21 and caged GTP with flash photolysis.&quot;&nbsp;</span><i style="font-family: Arial, sans-serif; font-size: 13px;">Proceedings of the National Academy of Sciences</i><span style="font-family: Arial, sans-serif; font-size: 13px;">&nbsp;86.20 (1989): 7687-7690.</span>

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