Ca2+ channel agonist 1

  • CAT Number: I001538
  • CAS Number: 1402821-24-2
  • Molecular Formula: C19H26N6O
  • Molecular Weight: 354.45
  • Purity: ≥95%
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Ca2+ channel agonist 1 (Cat No.: I001538) is an N-type Ca2+ channel agonist and Cdk2 inhibitor, with EC50 of 14.23 μM and 3.34 μM, respectively. potentially curative. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Catalog Number I001538
CAS Number 1402821-24-2
Molecular Formula

C19H26N6O

Purity 95%
Target Calcium Channel, CDK
Solubility 10 mM in DMSO
Storage Store at -20°C
IC50 14.23 uM (EC50, Ca2+ channel) 3.34 uM (EC50, cdk2)
IUPAC Name (2R)-2-[[6-(benzylamino)-9-propylpurin-2-yl]amino]butan-1-ol
InChI InChI=1S/C19H26N6O/c1-3-10-25-13-21-16-17(20-11-14-8-6-5-7-9-14)23-19(24-18(16)25)22-15(4-2)12-26/h5-9,13,15,26H,3-4,10-12H2,1-2H3,(H2,20,22,23,24)/t15-/m1/s1
InChIKey LKXPLOHGQSEPEM-OAHLLOKOSA-N
SMILES CCCN1C=NC2=C(N=C(N=C21)NC(CC)CO)NCC3=CC=CC=C3
Reference

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<br>[1]. Liang M, et al. Synthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist. ACS Med Chem Lett. 2012 Oct 1;3(12):985-990.

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