For research use only. Not for therapeutic Use.
Bufuralol hydrochloride（Cat No.:R003109）is a non-selective β-adrenergic receptor blocker with intrinsic sympathomimetic activity, making it useful in cardiovascular pharmacology research. It is commonly employed as a probe substrate for cytochrome P450 2D6 (CYP2D6), a key enzyme in drug metabolism, allowing detailed study of enzyme kinetics, polymorphisms, and drug–drug interactions. Bufuralol hydrochloride helps researchers investigate β-adrenergic regulation of cardiac function, arrhythmias, and hypertension, as well as CYP2D6-related metabolic variability. Its dual role as a β-blocker and metabolic probe makes it a valuable tool in cardiovascular and pharmacogenomic research.
| CAS Number | 60398-91-6 |
| Synonyms | 2-(tert-butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethanol;hydrochloride |
| Molecular Formula | C16H24ClNO2 |
| Purity | ≥95% |
| IUPAC Name | 2-(tert-butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethanol;hydrochloride |
| InChI | InChI=1S/C16H23NO2.ClH/c1-5-11-7-6-8-12-9-14(19-15(11)12)13(18)10-17-16(2,3)4;/h6-9,13,17-18H,5,10H2,1-4H3;1H |
| InChIKey | KJBONRGCLLBWCJ-UHFFFAOYSA-N |
| SMILES | CCC1=CC=CC2=C1OC(=C2)C(CNC(C)(C)C)O.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
