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BTSA1

BTSA1

  • CAT Number: I014278
  • CAS Number: 314761-14-3
  • Molecular Formula: C21H14N6OS2
  • Molecular Weight: 430.51
  • Purity: ≥95%
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BTSA1（Cat No.:I014278） is a potent activator of the BAX protein, a key regulator of apoptosis (programmed cell death). It exhibits high affinity and specificity for the N-terminal activation site of BAX, leading to conformational changes that trigger BAX-mediated apoptosis. BTSA1 has shown significant efficacy in promoting apoptosis specifically in leukemia cell lines and patient samples, while sparing healthy cells.

Catalog Number I014278
CAS Number 314761-14-3
Molecular Formula

C21H14N6OS2

Purity 95%
Target Bcl-2 modulator
Solubility Soluble in DMSO
Storage 2-8°C
IUPAC Name 5-phenyl-2-(4-phenyl-1,3-thiazol-2-yl)-4-(1,3-thiazol-2-yldiazenyl)-1H-pyrazol-3-one
InChI InChI=1S/C21H14N6OS2/c28-19-18(24-25-20-22-11-12-29-20)17(15-9-5-2-6-10-15)26-27(19)21-23-16(13-30-21)14-7-3-1-4-8-14/h1-13,26H
InChIKey CTRCXGFSYFTJIW-UHFFFAOYSA-N
SMILES C1=CC=C(C=C1)C2=CSC(=N2)N3C(=O)C(=C(N3)C4=CC=CC=C4)N=NC5=NC=CS5
Reference

</br>[1] Reyna DE, et al. Cancer Cell. 2017, 32(4):490-505.</br>

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