CONTACT US
Home > Isotope Labeled Compounds>Other Isotope Labeled Compounds> > BRD7116
BRD7116

BRD7116

  • CAT Number: I003173
  • CAS Number: 329059-55-4
  • Molecular Formula: C₂₈H₃₆N₂O₄S
  • Molecular Weight: 496.66
  • Purity: ≥95%
Inquiry Now

BRD7116 (Cat No.: I003173) is a potent compound that competitively binds to bacterial DNA gyrase. It exhibits significant activity against LSCe cells, with an EC50 value of 200 nM, making it a promising candidate for leukemia treatment. Additionally, BRD7116 demonstrates non-autonomous anti-leukemia activity, suggesting its potential for combination therapies. For further information or specific inquiries regarding BRD7116, please feel free to contact us.

Catalog Number I003173
CAS Number 329059-55-4
Synonyms

N,N/’-(sulfonyldi-4,1-phenylene)<em>bis</em>[2,2,3,3-tetramethyl-cyclopropanecarboxamide

Molecular Formula

C₂₈H₃₆N₂O₄S

Purity 95%
Target Cancer stem cell
Solubility DMSO: ≥ 48 mg/mL
Storage 2-8°C
IC50 200 nM (EC50, for LSCe cells)
IUPAC Name 2,2,3,3-tetramethyl-N-[4-[4-[(2,2,3,3-tetramethylcyclopropanecarbonyl)amino]phenyl]sulfonylphenyl]cyclopropane-1-carboxamide
InChI InChI=1S/C28H36N2O4S/c1-25(2)21(26(25,3)4)23(31)29-17-9-13-19(14-10-17)35(33,34)20-15-11-18(12-16-20)30-24(32)22-27(5,6)28(22,7)8/h9-16,21-22H,1-8H3,(H,29,31)(H,30,32)
InChIKey UHXFWAHRAMUDLJ-UHFFFAOYSA-N
SMILES CC1(C(C1(C)C)C(=O)NC2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)C4C(C4(C)C)(C)C)C
Reference

<p style=/line-height:25px/>
<br>[1]. Hartwell KA, et al. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat Chem Biol. 2013 Dec;9(12):840-848
</p>

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!