Boc-n-(2-hydroxyethyl)piperazine

• CAT Number: R074213
• CAS Number: 77279-24-4
• PubChem Substance ID: 735736
• Molecular Formula: C11H22N2O3
• Molecular Weight: 230.31
• Purity: ≥95%
• IUPAC Name: tert-butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate
• InChI: InChI=1S/C11H22N2O3/c1-11(2,3)16-10(15)13-6-4-12(5-7-13)8-9-14/h14H,4-9H2,1-3H3
• InChIKey: VRXIOAYUQIITBU-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCN(CC1)CCO

Boc-N-(2-hydroxyethyl)piperazine（Cat No.:R074213）is a functionalized piperazine derivative widely used as an intermediate in medicinal chemistry and drug discovery. It features a piperazine core substituted with a 2-hydroxyethyl side chain on one nitrogen and a tert-butoxycarbonyl (Boc) protecting group on the other. The Boc group stabilizes the molecule and facilitates selective deprotection in synthesis workflows. The hydroxyethyl moiety offers a reactive handle for further functionalization, enabling the design of diverse pharmacophores. This compound is frequently employed in the synthesis of CNS-active agents, kinase inhibitors, and other bioactive molecules.