For research use only. Not for therapeutic Use.
BIIL-260 hydrochloride（Cat No.:I018171）is a potent, selective antagonist of the leukotriene B4 (LTB4) receptor BLT1, a key mediator of inflammatory responses. By blocking LTB4 signaling, it reduces neutrophil activation, chemotaxis, and cytokine release, making it highly relevant in inflammation and immunology research. Preclinical and clinical studies have explored its potential in treating asthma, chronic obstructive pulmonary disease (COPD), and other inflammatory disorders. The hydrochloride salt form enhances solubility and stability for laboratory use. BIIL-260 hydrochloride is a valuable tool for investigating leukotriene pathways and immune-mediated diseases.
| CAS Number | 192581-24-1 |
| Synonyms | 4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidamide;hydrochloride |
| Molecular Formula | C30H31ClN2O3 |
| Purity | ≥95% |
| IUPAC Name | 4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidamide;hydrochloride |
| InChI | InChI=1S/C30H30N2O3.ClH/c1-30(2,24-8-12-26(33)13-9-24)25-10-16-28(17-11-25)35-20-22-5-3-4-21(18-22)19-34-27-14-6-23(7-15-27)29(31)32;/h3-18,33H,19-20H2,1-2H3,(H3,31,32);1H |
| InChIKey | KYFHIWXKXUSXKB-UHFFFAOYSA-N |
| SMILES | CC(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCC3=CC=CC(=C3)COC4=CC=C(C=C4)C(=N)N.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
