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Bictegravir - CAS 1611493-60-7

Bictegravir(CAT: I004238) also known as GS-9883, is a potent, unboosted, once-Daily HIV-1 Integrase Strand Transfer Inhibitor (INSTI) with improved pharmacokinetics and in vitro resistance profile. Bictegravir is currently in Phase 3 trials. This product is used for medical research and development.

Catalog Number: I004238

CAS Number: 1611493-60-7

PubChem Substance ID:355035962

Molecular Formula: C21H18F3N3O5

Molecular Weight:449.3862

Purity: ≥95%

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* For research use only. Not for human or veterinary use.

Synonym

SynonymsGS-9883; GS 9883; GS9883; GS-9883-01; Bictegravir;(2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1/’,2/’:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide

Property

Molecular Formula: C21H18F3N3O5
Molecular Weight449.3862
Target:HIV-1 Integrase Strand Transfer Inhibitor
SolubilitySoluble in DMSO
Purity≥95%
Storage0 - 4 °C for short term or -20 °C for long term

Computed Descriptor

IUPAC Name(1S,11R,13R)-5-hydroxy-3,6-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-12-oxa-2,9-diazatetracyclo[11.2.1.02,11.04,9]hexadeca-4,7-diene-7-carboxamide
InChIInChI=1S/C21H18F3N3O5/c22-9-3-14(23)12(15(24)4-9)6-25-20(30)13-7-26-8-16-27(10-1-2-11(5-10)32-16)21(31)17(26)19(29)18(13)28/h3-4,7,10-11,16,29H,1-2,5-6,8H2,(H,25,30)/t10-,11+,16+/m0/s1
InChIKeySOLUWJRYJLAZCX-LYOVBCGYSA-N
SMILESO=C(C1=CN(C2=C(O)C1=O)C[C@@]3([H])O[C@](C4)([H])CC[C@]4([H])N3C2=O)NCC5=C(F)C=C(F)C=C5F