CONTACT US
Home > Inhibitors/Agonists> > BI 689648
BI 689648

BI 689648

  • CAT Number: I013079
  • CAS Number: 1633009-87-6
  • Molecular Formula: C₁₆H₁₈N₄O₂
  • Molecular Weight: 298.34
  • Purity: ≥95%
Inquiry Now

BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively.

Catalog Number I013079
CAS Number 1633009-87-6
Molecular Formula

C₁₆H₁₈N₄O₂

Purity 95%
Target Cytochrome P450
Solubility DMSO: 30 mg/mL
IUPAC Name 6-[5-(methoxymethyl)pyridin-3-yl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
InChI InChI=1S/C16H18N4O2/c1-22-10-11-5-13(8-18-7-11)14-6-12-3-2-4-20(16(17)21)15(12)19-9-14/h5-9H,2-4,10H2,1H3,(H2,17,21)
InChIKey DJFDCVNQDFICKV-UHFFFAOYSA-N
SMILES COCC1=CN=CC(=C1)C2=CC3=C(N=C2)N(CCC3)C(=O)N
Reference

[1]. Weldon SM, et al. Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates. J Pharmacol Exp Ther. 2016 Oct;359(1):142-50.

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!