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Betahistine 2HCl

Betahistine 2HCl

  • CAT Number: A001166
  • CAS Number: 5579-84-0
  • Molecular Formula: C8H12N2.2HCl
  • Molecular Weight: 209.12
  • Purity: ≥95%
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Betahistine is a histamine H3 receptor inhibitor with IC50 of 1.9 μM.<br>Betahistine progressively enhances cAMP formation with a maximal effect, observed up to 10 nM, in CHO(H3R) cells incubated with 3 μM forskolin. In contrast, at concentrations higher than 10 nM betahistine progressively inhibits cAMP formation in CHO(H3R) cells incubated with 3 μM forskolin. Betahistine progressively reduces A23187-evoked [<br>Betahistine (< 30 mg/kg) increases t-MeHA levels in a dose-dependent manner with an ED50 of 2 mg/kg and a maximal effect of ∼35% reached at 30 mg/kg in mouse brain.

Catalog Number A001166
CAS Number 5579-84-0
Molecular Formula

C8H12N2.2HCl

Purity 95%
Target Histamine Receptor
Solubility Soluble in DMSO > 10 mM
Storage 3 years -20C powder

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