(beta)-Apo-13-carotenone

• CAT Number: I013397
• CAS Number: 17974-57-1
• Molecular Formula: C₁₈H₂₆O
• Molecular Weight: 258.4
• Purity: ≥95%
• Target: Others
• Solubility: DMSO
• IUPAC Name: (3E,5E,7E)-6-methyl-8-(2,6,6-trimethylcyclohexen-1-yl)octa-3,5,7-trien-2-one
• InChI: InChI=1S/C18H26O/c1-14(8-6-10-16(3)19)11-12-17-15(2)9-7-13-18(17,4)5/h6,8,10-12H,7,9,13H2,1-5H3/b10-6+,12-11+,14-8+
• InChIKey: UBTNVRPIHJRBCI-LUXGDSJYSA-N
• SMILES: CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=O)C)C

13-apo-beta-carotenone (CAT: I013397) is an apo-carotenoid compound that is derived from the oxidative degradation of the beta, beta-carotene skeleton at the 13-position. It belongs to the class of apo carotenoids and is characterized by the presence of an enone functional group. Apo carotenoids are carotenoid compounds that have undergone structural modifications, such as cleavage or oxidation, resulting in the loss of one or more carbon-carbon double bonds. 13-apo-beta-carotenone represents one of the degradation products of beta-carotene and may have biological activities or applications related to its unique structure and properties.

Reference

[1]. Eroglu A, et al. The eccentric cleavage product of β-carotene, β-apo-13-carotenone, functions as an antagonist of RXRα. Arch Biochem Biophys. 2010 Dec 1;504(1):11-6.
[2]. Sun J, et al. β-Apo-13-carotenone regulates retinoid X receptor transcriptional activity through tetramerization of the receptor. J Biol Chem. 2014 Nov 28;289(48):33118-24.
[3]. Wang CX, et al. Actions of β-apo-carotenoids in differentiating cells: differential effects in P19 cells and 3T3-L1 adipocytes. Arch Biochem Biophys. 2015 Apr 15;572:2-10.