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BAY 43-9006, Free base

BAY 43-9006, Free base

  • CAT Number: A000154
  • CAS Number: 284461-73-0
  • Molecular Formula: C₂₁H₁₆ClF₃N₄O₃
  • Molecular Weight: 464.82
  • Purity: ≥95%
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Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.

Catalog Number A000154
CAS Number 284461-73-0
Molecular Formula

C₂₁H₁₆ClF₃N₄O₃

Purity 95%
Target PDGFR
Solubility >23.3mg/mL in DMSO
Storage Store at -20°C
InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
InChIKey MLDQJTXFUGDVEO-UHFFFAOYSA-N
SMILES CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F

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