Azido-PEG2-hydrazide-Boc

• CAT Number: I015797
• CAS Number: 2100306-56-5
• Molecular Formula: C12H23N5O5
• Molecular Weight: 317.34
• Purity: ≥95%
• Synonyms: tert-butyl N-[3-[2-(2-azidoethoxy)ethoxy]propanoylamino]carbamate
• InChI: InChI=1S/C12H23N5O5/c1-12(2,3)22-11(19)16-15-10(18)4-6-20-8-9-21-7-5-14-17-13/h4-9H2,1-3H3,(H,15,18)(H,16,19)
• InChIKey: JYNHRXFEKXQQDG-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NNC(=O)CCOCCOCCN=[N+]=[N-]

Azido-PEG2-hydrazide-Boc（Cat No.:I015797）is a compact heterobifunctional linker designed for precise bioconjugation. It carries a terminal azide group for copper-catalyzed or strain-promoted click chemistry with alkynes, and a Boc-protected hydrazide that can be selectively deprotected to react with aldehydes or ketones, forming stable hydrazone linkages. The PEG2 spacer provides hydrophilicity, flexibility, and reduced steric hindrance, improving solubility and accessibility in aqueous and organic systems. This reagent is widely used in chemical biology, probe design, proteomics, and drug discovery, supporting modular, orthogonal strategies for controlled molecular assembly and functionalization.