Azaspiracid-1

• CAT Number: R067736
• CAS Number: 214899-21-5
• Molecular Formula: C47 H71 N O12
• Molecular Weight: 842.07
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: InChI=1S/C47H71NO12/c1-26-18-36-41-38(24-45(58-41)30(5)17-27(2)25-48-45)56-44(22-26,55-36)23-29(4)40-28(3)19-32(7)47(52,59-40)42(51)37-21-35-34(53-37)20-31(6)46(57-35)16-15-43(60-46)14-10-12-33(54-43)11-8-9-13-39(49)50/h8,10-11,14,26-28,30-38,40-42,48,51-52H,4,9,12-13,15-25H2,1-3,5-7H3,(H,49,50)/b11-8+/t26-,27+,28+,30-,31+,32-,33-,34+,35+,36+,37-,38+,40+,41+,42+,43+,44-,45-,46-,47-/m1/s1
• InChI: AHFHSIVCLPAESC-SJVADWSCSA-N
• InChIKey: CC1CC2C3C(CC4(O3)C(CC(CN4)C)C)OC(C1)(O2)CC(=C)C5C(CC(C(O5)(C(C6CC7C(O6)CC(C8(O7)CCC9(O8)C=CCC(O9)C=CCCC(=O)O)C)O)O)C)C
• SMILES: C[C@@H]1C[C@H]2[C@H]3[C@H](C[C@@]4(O3)[C@@H](C[C@@H](CN4)C)C)O[C@@](C1)(O2)CC(=C)[C@@H]5[C@H](C[C@H]([C@@](O5)([C@H]([C@H]6C[C@H]7[C@@H](O6)C[C@@H]([C@@]8(O7)CC[C@@]9(O8)C=CC[C@H](O9)/C=C/CCC(=O)O)C)O)O)C)C

Azaspiracid-1（Cat No.:214899-21-5）, is a naturally occurring marine toxin produced by certain species of microscopic dinoflagellates. It is associated with seafood poisoning events, causing symptoms such as vomiting, diarrhea, and nausea in humans who consume contaminated shellfish. Azaspiracid-1’s complex chemical structure and toxic effects have led to its classification as a harmful algal bloom toxin. Monitoring and regulating shellfish harvesting areas for the presence of azaspiracids are crucial for ensuring food safety.

Reference

1.Ito, Emiko, et al. "Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland." Toxicon 38.7 (2000): 917-930.
2.Román, Yolanda, et al. "Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets." Cellular signalling 14.8 (2002): 703-716.
3.Colman, Jamie R., et al. "Teratogenic effects of azaspiracid-1 identified by microinjection of Japanese medaka (Oryzias latipes) embryos." Toxicon 45.7 (2005): 881-890.