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Atuveciclib S-Enantiomer

Atuveciclib S-Enantiomer

  • CAT Number: I020003
  • CAS Number: 250279-81-1
  • Molecular Formula: C₁₈H₁₈FN₅O₂S
  • Molecular Weight: 387.43
  • Purity: ≥95%
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Atuveciclib S-Enantiomer（Cat No.:I020003）, also known as BAY-1143572, is a highly potent and selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). It is used in the treatment of cancer. Atuveciclib S-Enantiomer has demonstrated potent anti-tumor activity in preclinical studies and is currently being investigated in clinical trials for the treatment of various types of cancer. It inhibits the growth of CDK4/6-dependent tumor cell lines and induces cell cycle arrest in the G1 phase, leading to decreased proliferation of cancer cells.

Catalog Number I020003
CAS Number 250279-81-1
Molecular Formula

C₁₈H₁₈FN₅O₂S

Purity 95%
Reference

[1]. Lücking U, et al. Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer. ChemMedChem. 2017 Nov 8;12(21):1776-1793.

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