For research use only. Not for therapeutic Use.
ASP4132（Cat No.:I022533）is a potent and selective activator of AMP-activated protein kinase (AMPK), a central regulator of cellular energy homeostasis. By stimulating AMPK, ASP4132 promotes catabolic pathways, inhibits anabolic signaling, and suppresses mTOR activity, making it highly relevant in studies of metabolism, cancer, and aging. Research indicates that ASP4132 exerts antitumor effects by impairing cancer cell growth and survival while also demonstrating potential in metabolic and neurodegenerative disease models. Its specificity and activity profile make ASP4132 a valuable tool for biomedical and pharmacological research.
| CAS Number | 1640294-30-9 |
| Synonyms | [6-[1-[(6-methoxypyridin-3-yl)methyl]piperidin-4-yl]-1H-benzimidazol-2-yl]-[4-[[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone;4-methylbenzenesulfonic acid |
| Molecular Formula | C46H51F3N6O8S2 |
| Purity | ≥95% |
| IUPAC Name | [6-[1-[(6-methoxypyridin-3-yl)methyl]piperidin-4-yl]-1H-benzimidazol-2-yl]-[4-[[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone;4-methylbenzenesulfonic acid |
| InChI | InChI=1S/C32H35F3N6O2.2C7H8O3S/c1-43-29-9-4-23(19-36-29)21-39-12-10-24(11-13-39)25-5-8-27-28(18-25)38-30(37-27)31(42)41-16-14-40(15-17-41)20-22-2-6-26(7-3-22)32(33,34)35;2*1-6-2-4-7(5-3-6)11(8,9)10/h2-9,18-19,24H,10-17,20-21H2,1H3,(H,37,38);2*2-5H,1H3,(H,8,9,10) |
| InChIKey | KDMGCEXVMOJAAC-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.COC1=NC=C(C=C1)CN2CCC(CC2)C3=CC4=C(C=C3)N=C(N4)C(=O)N5CCN(CC5)CC6=CC=C(C=C6)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
