For research use only. Not for therapeutic Use.
ARN-21934（Cat No.:I044669）is a selective, allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4), a receptor involved in regulating neurotransmission in the central nervous system. By enhancing mGluR4 signaling, ARN-21934 exhibits potential therapeutic benefits for neurological and psychiatric disorders, particularly Parkinson’s disease, anxiety, and pain. Unlike orthosteric agonists, it offers subtype selectivity and reduced side effects through its allosteric mechanism. ARN-21934 has shown promise in preclinical models by improving motor function and reducing neuroinflammation, making it a valuable compound for advancing neuropharmacological research.
| CAS Number | 2230854-93-8 |
| Synonyms | 4-N-[4-(dimethylamino)phenyl]-2-pyridin-4-yl-5,6,7,8-tetrahydroquinazoline-4,6-diamine |
| Molecular Formula | C21H24N6 |
| Purity | ≥95% |
| IUPAC Name | 4-N-[4-(dimethylamino)phenyl]-2-pyridin-4-yl-5,6,7,8-tetrahydroquinazoline-4,6-diamine |
| InChI | InChI=1S/C21H24N6/c1-27(2)17-6-4-16(5-7-17)24-21-18-13-15(22)3-8-19(18)25-20(26-21)14-9-11-23-12-10-14/h4-7,9-12,15H,3,8,13,22H2,1-2H3,(H,24,25,26) |
| InChIKey | CKXSRLUXTFDZCF-UHFFFAOYSA-N |
| SMILES | CN(C)C1=CC=C(C=C1)NC2=NC(=NC3=C2CC(CC3)N)C4=CC=NC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
