Antineoplaston A 10

• CAT Number: I002419
• CAS Number: 91531-30-5
• Molecular Formula: C13H14N2O3
• Molecular Weight: 246.26
• Purity: ≥95%
• Synonyms: ANP-A-10; ANPA-10; ANP A 10; ANPA 10;;N-[(3S)-2,6-dioxopiperidin-3-yl]-2-phenylacetamide
• Target: Ras inhibitor
• Solubility: Soluble in DMSO
• Storage: 2-8°C
• IUPAC Name: N-[(3S)-2,6-dioxopiperidin-3-yl]-2-phenylacetamide
• InChI: InChI=1S/C13H14N2O3/c16-11-7-6-10(13(18)15-11)14-12(17)8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,14,17)(H,15,16,18)/t10-/m0/s1
• InChIKey: OQGRFQCUGLKSAV-JTQLQIEISA-N
• SMILES: C1CC(=O)NC(=O)C1NC(=O)CC2=CC=CC=C2

AntineoplastonA10 (Cat No.: I002419) is a naturally occurring substance in the human body and can be potentially used in the treatment of glioma, lymphoma, astrocytoma and breast cancer. The main active ingredient of AnChemicalbook tineoplastonA10 (Phenylacetylglutamine, PG) inhibits RAS and promotes its apoptosis.

Reference

1:Immune modulatory potentials of antineoplaston A-10 in breast cancer patients. Badria F, Mabed M, El-Awadi M, Abou-Zeid L, Al-Nashar E, Hawas S.Cancer Lett. 2000 Aug 31;157(1):57-63. PMID: 10893443 2:Potential utility of antineoplaston A-10 levels in breast cancer. Badria F, Mabed M, Khafagy W, Abou-Zeid L.Cancer Lett. 2000 Jul 3;155(1):67-70. PMID: 10814881 3:The inhibitory effect of the combination of antineoplaston A-10 injection with a small dose of cis-diamminedichloroplatinum on cell and tumor growth of human hepatocellular carcinoma. Tsuda H, Sugihara S, Nishida H, Hara H, Eriguchi N, Ishii K, Sasaki K, Yoshimura S, Tanaka N.Jpn J Cancer Res. 1992 May;83(5):527-31. PMID: 1377669 4:The anticancer effect of antineoplaston A-10 on human breast cancer serially transplanted to athymic mice. Hashimoto K, Koga T, Shintomi Y, Tanaka M, Kakegawa T, Tsuda H, Hara H.Nihon Gan Chiryo Gakkai Shi. 1990 Jan 20;25(1):1-5. PMID: 2157780 5:Inhibitory effect of antineoplaston A-10 on breast cancer transplanted to athymic mice and human hepatocellular carcinoma cell lines. The members of Antineoplaston Study Group. Tsuda H.Kurume Med J. 1990;37(2):97-104. PMID: 2175003 Free Article6:Chemopreventive effect of antineoplaston A-10 on urethane-induced pulmonary neoplasm in mice. Eriguchi N, Hara H, Yoshida H, Nishida H, Nakayama T, Ohishi K, Tsuda H, Inoue S, Ikeda I.Nihon Gan Chiryo Gakkai Shi. 1988 Jul 20;23(7):1560-5. No abstract available. PMID: 3183462