Anti-amyloid agent-1

• CAT Number: I041161
• CAS Number: 1396778-73-6
• Molecular Formula: C21H17F3N2O3
• Molecular Weight: 402.37
• Purity: ≥95%
• Synonyms: 1-[3-[3-(benzylamino)-4-nitrophenyl]phenyl]-2,2,2-trifluoroethanol
• InChI: InChI=1S/C21H17F3N2O3/c22-21(23,24)20(27)17-8-4-7-15(11-17)16-9-10-19(26(28)29)18(12-16)25-13-14-5-2-1-3-6-14/h1-12,20,25,27H,13H2
• InChIKey: ASHWETLKGUZRJW-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CNC2=C(C=CC(=C2)C3=CC(=CC=C3)C(C(F)(F)F)O)[N+](=O)[O-]

Anti-amyloid agent-1 (Cat No.: I041161) is a small molecule or experimental therapeutic designed to inhibit the formation or promote the clearance of amyloid fibrils, which are protein aggregates implicated in neurodegenerative diseases such as Alzheimer’s disease. This agent may function by stabilizing native protein conformations, blocking misfolded intermediates, or enhancing amyloid degradation pathways. Anti-amyloid agent-1 is used in research to explore mechanisms of amyloid pathology and assess potential disease-modifying strategies aimed at reducing cognitive decline and neuronal damage associated with amyloid accumulation.

Reference

[1]. Mark A. Reed, et al. Anti-amyloid compounds and methods. Patent WO2012119035A1.