Anhydrotetracycline Hydrochloride

  • CAT Number: R013284
  • CAS Number: 13803-65-1
  • Molecular Formula: C22H23ClN2O7
  • Molecular Weight: 462.883
  • Purity: ≥95%
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Anhydrotetracycline hydrochloride(CAT: R013284) is a derivative of tetracycline, an antibiotic compound. Its mode of action and pharmacological effects involve its interactions with bacterial ribosomes, leading to the inhibition of protein synthesis in bacteria. Pharmacologically, anhydrotetracycline hydrochloride exhibits antibiotic properties, making it effective against a wide range of bacterial infections.

Catalog Number R013284
CAS Number 13803-65-1
Synonyms

(4S,4aS,12aS)-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide Hydrochloride;

Molecular Formula

C22H23ClN2O7

Purity 95%
Target Transcription Factors
Solubility Soluble in DMSO
Storage Store at -20°C
IUPAC Name (4S,4aS,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide;hydrochloride
InChI InChI=1S/C22H22N2O7.ClH/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28;/h4-6,11,16,25-26,29,31H,7H2,1-3H3,(H2,23,30);1H/t11-,16-,22-;/m0./s1
InChIKey SPFAOPCHYIJPHJ-WPJNXPDPSA-N
SMILES CC1=C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C.Cl
Reference

Gossen, Manfred. /Anhydrotetracycline, a Novel Effector for Tetra./ <em>Nucleic Acids</em> Research 21.18 (1993): 4411-412. Ncbi.gov. Web. 3 May 2013.Skerra, Arne. /Use of the tetracycline promoter for the tightly regulated production of a murine antibody fragment in&lt; i&gt; Escherichia coli</span></p>

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