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AN-2690

AN-2690

  • CAT Number: I002281
  • CAS Number: 174671-46-6
  • Molecular Formula: C7H6BFO2
  • Molecular Weight: 151.93
  • Purity: ≥95%
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AN-2690 (Cat.No:I002281) is an antifungal agent used in topical treatment of onychomycosis, a fungal infection of the nail. It inhibits fungal protein synthesis by targeting squalene epoxidase. AN-2690 has shown to be effective against various dermatophytes, yeasts, and molds. It is a broad-spectrum antifungal agent with low systemic absorption, making it a promising therapeutic option.

Catalog Number I002281
CAS Number 174671-46-6
Molecular Formula

C7H6BFO2

Purity 95%
Target Antibiotic
Solubility 10 mM in DMSO
Storage Store at -20°C
IUPAC Name 5-fluoro-1-hydroxy-3H-2,1-benzoxaborole
InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2
InChIKey LFQDNHWZDQTITF-UHFFFAOYSA-N
SMILES B1(C2=C(CO1)C=C(C=C2)F)O
Reference

</br>1:Tavaborole (AN-2690) for the treatment of onychomycosis of the toenail in adults. Gupta AK, Daigle D.Expert Rev Anti Infect Ther. 2014 Jul;12(7):735-42. doi: 10.1586/14787210.2014.915738. Epub 2014 Jun 4. Review. PMID: 24894552 </br>2:AN-2690, a novel antifungal for the topical treatment of onychomycosis. Barak O, Loo DS.Curr Opin Investig Drugs. 2007 Aug;8(8):662-8. Review. PMID: 17668368

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