Amitriptyline-d3 hydrochloride

• CAT Number: R006678
• CAS Number: 342611-00-1
• Molecular Formula: C20H21D3ClN
• Molecular Weight: 316.88
• Purity: ≥95%
• Synonyms: N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)-N-(trideuteriomethyl)propan-1-amine;hydrochloride
• InChI: InChI=1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H/i1D3
• InChIKey: KFYRPLNVJVHZGT-NIIDSAIPSA-N
• SMILES: [2H]C([2H])([2H])N(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

Amitriptyline-d3 hydrochloride（Cat No.:R006678）is a deuterated analog of amitriptyline, a tricyclic antidepressant commonly used to treat depression, anxiety, and chronic pain. In this compound, three hydrogen atoms are replaced with deuterium to improve stability and facilitate precise quantification in mass spectrometry. The hydrochloride salt enhances solubility and ease of formulation for analytical use. Amitriptyline-d3 is primarily employed as an internal standard in bioanalytical assays, supporting pharmacokinetic studies, therapeutic drug monitoring, and drug metabolism research. It enables accurate measurement of amitriptyline levels in biological samples for clinical and research applications.