AMI-5

• CAT Number: R024390
• CAS Number: 17372-87-1
• Molecular Formula: C₂₀H₆Br₄Na₂O₅
• Molecular Weight: 691.85
• Purity: ≥95%
• Synonyms: 11445 Red; 11731 Red; 1903 Yellow Pink; ABCO Eosin; Abbey Eosin; Acid Red 87; Acid Red 87-39014; Aizen Eosine; Aizen Eosine GH; Aizen Eosine GH 35%-L; Basacid Red 316; Bromo 4D; Bromo 4DC; Bromo 4DL; Bromo B; Bromo FL; Bromo JPS; Bromo TS; Bromo X 10
• Target: Histone Methyltransferase
• Solubility: Soluble in DMSO
• Storage: Store at -20C
• InChI: InChI=1S/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2*+1/p-2
• InChIKey: SEACYXSIPDVVMV-UHFFFAOYSA-L
• SMILES: C1=CC=C(C(=C1)C2=C3C=C(C(=O)C(=C3OC4=C(C(=C(C=C24)Br)[O-])Br)Br)Br)C(=O)[O-].[Na+].[Na+]

AMI-5 (Cat No.: R024390) is a selective small-molecule inhibitor of protein arginine methyltransferases (PRMTs), particularly targeting PRMT1. By blocking arginine methylation on histones and non-histone proteins, AMI-5 modulates epigenetic regulation and gene expression. It is commonly used in biochemical and cellular studies to explore the role of PRMTs in cancer, inflammation, and other diseases linked to aberrant methylation. AMI-5 serves as a valuable tool compound in epigenetics research, aiding the development of therapeutic strategies targeting methylation-dependent signaling pathways.