Alloxan Monohydrate

• CAT Number: R020394
• CAS Number: 2244-11-3
• Molecular Formula: C4H4N2O5
• Molecular Weight: 160.085
• Purity: ≥95%
• Synonyms: 2,4,5,6(1H,3H)-Pyrimidinetetrone Hydrate; 2,4,5,6(1H,3H)-Pyrimidinetetrone Monohydrate
• Storage: -20°C
• IUPAC Name: 1,3-diazinane-2,4,5,6-tetrone;hydrate
• InChI: InChI=1S/C4H2N2O4.H2O/c7-1-2(8)5-4(10)6-3(1)9;/h(H2,5,6,8,9,10);1H2
• InChIKey: DSXMTJRUNLATRP-UHFFFAOYSA-N
• SMILES: C1(=O)C(=O)NC(=O)NC1=O.O

Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.

Reference

1:Hypoglycemic effects of vanadium on alloxan monohydrate induced diabetic dogs. Kim JM, Chung JY, Lee SY, Choi EW, Kim MK, Hwang CY, Youn HY.J Vet Sci. 2006 Dec;7(4):391-5. PMID: 17106233 Free PMC Article2:Plasma atrial natriuretic peptide levels in rabbits with alloxan monohydrate-induced diabetes mellitus. Yeğen E, Akçay F, Yiğitoğlu MR, Celik I, Suzek H, Odabaşioğlu F.Jpn Heart J. 1995 Nov;36(6):789-95. PMID: 8627984 3:The importance of parasite load in the killing of Plasmodium vinckei in mice treated with Corynebacterium parvum or alloxan monohydrate. Cox FE, Millott SM.Parasitology. 1984 Dec;89 ( Pt 3):417-24. PMID: 6514377 4:Toxicity of sodium ascorbate and alloxan monohydrate to 3T3 mouse cells [proceedings]. Cope PA, Dawson M.J Pharm Pharmacol. 1978 Dec;30 Suppl:77P. No abstract available. PMID: 32336 5:Changes in the rats preference for saccharin and sodium chloride solutions following injection of alloxan monohydrate. Brookshire KH.J Comp Physiol Psychol. 1974 Dec;87(6):1061-8. No abstract available. PMID: 4443448 6:Effect of alloxan monohydrate on increased vascular permeability in sheep. Vegad JL.Indian J Exp Biol. 1972 May;10(3):232-3. No abstract available. PMID: 4119655