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Akuammigine

Akuammigine

  • CAT Number: R044480
  • CAS Number: 642-17-1
  • Molecular Formula: C21H24N2O3
  • Molecular Weight: 352.434
  • Purity: ≥95%
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<p>
<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Akuammigine (CAS&nbsp;642-17-1)&nbsp;is a natural alkaloid found in the herbs of Picralima nitida. Akuammigine shows antimalarial activity in vitro and competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors.</span></span></span></p>

Catalog Number R044480
CAS Number 642-17-1
Molecular Formula

C21H24N2O3

Purity 95%
Storage 3 years -20C powder
IUPAC Name methyl (1R,15S,16S,20S)-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate
InChI InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16-,19+/m0/s1
InChIKey GRTOGORTSDXSFK-BMYCAMMWSA-N
SMILES CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45
Reference

<p>
<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">1.Yang, Weimin, et al. &quot;Almitrine‐Raubasine combination for dementia.&quot;&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">Cochrane Database of Systematic Reviews</i>&nbsp;3 (2011).</span></span></span></p>

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