ADU-S100 enantiomer ammonium salt

• CAT Number: I046111
• Molecular Formula: C20H30N12O10P2S2
• Molecular Weight: 724.60
• Purity: ≥95%
• Synonyms: azane;(1R,6R,8R,9R,10S,15R,17R,18R)-8,17-bis(6-aminopurin-9-yl)-12-hydroxy-3-oxo-3-sulfanyl-12-sulfanylidene-2,4,7,11,13,16-hexaoxa-3λ5,12λ5-diphosphatricyclo[13.2.1.06,10]octadecane-9,18-diol
• IUPAC Name: azane;(1R,6R,8R,9R,10S,15R,17R,18R)-8,17-bis(6-aminopurin-9-yl)-12-hydroxy-3-oxo-3-sulfanyl-12-sulfanylidene-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.2.1.06,10]octadecane-9,18-diol
• InChI: InChI=1S/C20H24N10O10P2S2.2H3N/c21-15-9-17(25-3-23-15)29(5-27-9)19-12(32)13-8(38-19)2-36-42(34,44)40-14-11(31)7(1-35-41(33,43)39-13)37-20(14)30-6-28-10-16(22)24-4-26-18(10)30;;/h3-8,11-14,19-20,31-32H,1-2H2,(H,33,43)(H,34,44)(H2,21,23,25)(H2,22,24,26);2*1H3/t7-,8-,11-,12-,13-,14-,19-,20-,41?,42?;;/m1../s1
• InChIKey: VZYXAGGQHVUTHM-QYUKNOIISA-N
• SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)OP(=O)(OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C=NC7=C(N=CN=C76)N)O)OP(=S)(O1)O)S)O.N.N

ADU-S100 enantiomer ammonium salt（Cat No.:I046111）is a potent STING (stimulator of interferon genes) pathway agonist that activates innate immune responses through induction of type I interferons and pro-inflammatory cytokines. As a cyclic dinucleotide analog, it binds and stabilizes STING, promoting antitumor immunity and enhancing responses to immunotherapies. The enantiomer ammonium salt form improves solubility and formulation properties, making it suitable for in vitro and in vivo studies. ADU-S100 is widely used in cancer immunology research to explore mechanisms of immune activation and develop next-generation immunotherapeutic strategies.